Name: Jeroen C.W. Siero, PhD, Ir.
Position: Assistant Professor
Institute: University Medical Center Utrecht, Dept. Radiology, Utrecht, The Netherlands
Spinoza Center for Neuroimaging, Amsterdam, The Netherlands,
Cerebrovascular Reactivity using High Resolution MRI at 7T
My focus is on mapping fine-scale CVR properties using blood-oxygenation-level-dependent and arterial spin labelling MRI using blood gas manipulations. Examining fine-scale CVR can be of particular importance as it is hypothesized that disturbed capillary blood flow patterns might play a crucial role in small vessel disease and in the events preceding ischemic stroke. In addition, I am interested in how the cortical vascular organization and dynamics affects high-resolution functional BOLD fMRI and interpretation of local neurovascular coupling mechanisms.
· BOLD and ASL (f)MRI
· Ultra high-field MRI, 7 tesla
· Neurovascular coupling
· (Modelling of) biophysics and physiology of cerebral hemodynamics
· Cerebrovascular reactivity